"So here, then, is the first momentous change in the Western diet that may explain why it makes some people sick: Supplanting tested relationships to the whole foods with which we coevolved over many thousands of years, it asks our bodies now to relate to, and deal with, a very small handful of efficiently delivered nutrients that have been torn from their food context. Our ancient evolutionary relationship with the seeds of grasses and fruit of plants have given way, abruptly, to a rocky mariage with glucose and fructose."